Protein Details: Gap junction alpha-8 protein

Protein ID

ICDB_Pro_0623

Protein Name

Gap junction alpha-8 protein

Gene Name

GJA8

Organism

Ovis aries (Sheep)

Length

440 amino acids

AlphaFoldDB

AF-P55917-F1-model_v4.pdb

Function

Sequence

MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPGCENVCYDEAFPISHIRLWVLQIIFVSTPSLVYVGHAVHHVRMEEKRKEREAEELSQQSPGNGGERAPLAADQGSVKKSSSSSKGTKKFRLEGTLLRTYVCHIIFKTLFEVGFIVGHYFLYGFRILPLYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNILEMSHLGLKKIRSAFKRPVEQPLGEIPEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMVEASPLSAKPFSQFEEKVGPGPLGDLSRAYQETLPSYAQVGAQEGVEEEQPIEAAAEPEVGDKSQEAERVSTEGEETLAVLEEEKVEPPEVEKEAEKEETPPEKVSKQELTPEKAPSLCAELPGEDTRPLSRLSKASSRARSDDLTV

PDB Structures

6MHY 7JJP 7JLW 7JM9 7JMC

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Location

Detected in eye lens (at protein level) (PubMed:30542154). Eye lens (PubMed:8654111).

DOI ID

10.3109/02713689609007625; 10.1038/331721a0; 10.1038/s41586-018-0786-7

RefSeq

NP_001123510.1